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optical mapping bionano saphyr (BioNano Genomics)

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BioNano Genomics optical mapping bionano saphyr
Optical Mapping Bionano Saphyr, supplied by BioNano Genomics, used in various techniques. Bioz Stars score: 90/100, based on 1 PubMed citations. ZERO BIAS - scores, article reviews, protocol conditions and more
https://www.bioz.com/product/bionano+optical+maps/bionano+optical+maps/pmc12267650-24-3-3
Average 90 stars, based on 1 article reviews

optical mapping bionano saphyr - by Bioz Stars, 2026-10

90/100 stars

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Scaffolding:

Article Title: Telomere-to-telomere sheep genome assembly identifies variants associated with wool fineness.
Article Snippet: Ongoing efforts to improve sheep reference genome assemblies still leave many gaps and incomplete regions, resulting in a few common failures and errors in genomic studies.. Here, we report a 2.85-Gb gap-free telomere-to-telomere genome of a ram (T2T-sheep1.0), including all autosomes and the X and Y chromosomes.. This genome adds 220.05 Mb of previously unresolved regions and 754 new genes to the most updated reference assembly ARS-UI_Ramb_v3.0; it contains four types of repeat units (SatI, SatII, SatIII and CenY) in centromeric regions.

Sequencing:

Article Title:
Article Snippet: All paired-end libraries were sequenced on an Illumina NovaSeq 6000 system, generating 291 Gb (81 X coverage) of 150-nucleotide paired-end reads. .. We adopted a hierarchical sequencing approach to generate a high-quality reference genome for blackgrass from a single individual using PacBio long reads, BioNano optical maps, chromatin conformation capture sequencing (Hi-C) and paired Illumina short reads (Supplementary Figure 1). ..

Hi-C:

Article Title: The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution.
Article Snippet: .. We applied two sequential approaches to scaffold the contigs, first with 560 Gbp (L. cosentinii) and 722 Gbp (L. digitatus) of Bionano optical maps (based on 4.7 million and 5.4 million molecules for L. cosentinii and L. digitatus, respectively), then with 60.4 Gbp (L. cosentinii) and 53 Gbp (L. digitatus) of chromosome-level Illumina Hi-C data (Supplementary Data 1, Nature Communications | (2025) 16:4358 2 Supplementary Data 2, Supplementary Fig. 2). ..

Article Title: The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution
Article Snippet: .. Both genomes were assembled at the highest possible level, including both Bionano optical maps and Hi-C data, but the high level of assembly duplication and genome ploidy hindered the reconstruction process, resulting in a more fragmented and less contiguous product than expected. ..

other:

Article Title: Oryza genome evolution through a tetraploid lens
Article Snippet: We generated chromosome-level reference assemblies for nine tetraploid and two diploid wild Oryza species (Extended Data Table and Supplementary Note ) and extensively assessed them for quality and contiguity (with Bionano optical maps, genome assembly evaluation using BUSCO and the genome mapping rate) as described in Supplementary Note and Supplementary Tables – .

Article Title: The unexplored diversity of rough-seeded lupins provides rich genomic resources and insights into lupin evolution.
Article Snippet: Scaffolding with Bionano optical maps Bionano sequencing outputs were filtered to remove molecules <150 kbp in length before de novo assembly and alignment on the corresponding genome maps using Bionano Solve v3.7.1 (https:// bionanogenomics.com/support/).